Se quando accedi alla datasheet view di SharePoint 2010 con un sistema operativo Windows a 64 bit ti compare questo popup di avviso:
The list cannot be displayed in Datasheet view for one or more of the following reasons:
- A datasheet component compatible with Microsoft SharePoint Foundation is not installed.
- Your Web browser does not support ActiveX controls.
- A component is not properly configured for 32-bit or 64-bit support.

è perché ti mancano i 2007 Office System Driver: Data Connectivity Components.
La datasheet view funziona solo con Internet Explorer